Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.100 GeneticVariation group BEFREE Obtained results confirm the presence of an association between 5-HT2AR and BDNF genes and the susceptibility to EDs. 31746551 2020
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.090 GeneticVariation group BEFREE Support was found for the efficacy and effectiveness of CBT-E for the full spectrum of eating disorders, with respect to reducing eating disorder behaviors and core psychopathology. 31840285 2020
Entrez Id: 100653365
Gene Symbol: BED
BED
0.050 Biomarker group BEFREE Balanced sporting activity should be considered a resource in the treatment of eating disorders (ED), in particular of the BED and in obesity but also, if conducted and guided by expert preparers and rehabilitators, in some forms of anorexia and in bulimia.</p> Objective: However, when physical activity becomes compulsive, an end in itself and which interferes predominantly in daily activities, aimed essentially at energy consumption to force weight loss up to marked decay, it becomes a pathological instrument, an elimination course, a form purging and falls within the diagnostic criteria in bulimia and anorexia nervosa. 31684854 2020
Entrez Id: 10163
Gene Symbol: WASF2
WASF2
0.030 GeneticVariation group BEFREE Data from a longitudinal sample of female twins were selected: measures of risk for DE from Wave 1 (N = 699, 351 pairs, aged 12-15 years), and the Eating Disorder Examination (EDE) and Children's Anxiety Sensitivity Index (CASI) from Wave 2 (N = 669, 338 pairs, aged 16-19 years). 31429983 2020
Entrez Id: 8936
Gene Symbol: WASF1
WASF1
0.020 Biomarker group BEFREE Data from a longitudinal sample of female twins were selected: measures of risk for DE from Wave 1 (N = 699, 351 pairs, aged 12-15 years), and the Eating Disorder Examination (EDE) and Children's Anxiety Sensitivity Index (CASI) from Wave 2 (N = 669, 338 pairs, aged 16-19 years). 31429983 2020
Entrez Id: 8444
Gene Symbol: DYRK3
DYRK3
0.010 Biomarker group BEFREE </p> Results:In general, nutrition is experienced, not only by athletes themselves but also by technicians and coaches, as a tool for improving performance and as such assimilated to an aspect of training but in the presence of factors of vulnerability towards the ED by of the young athletes the exaggerated tendency to manipulate the weight can determine the appearance of an eating disorder or of the so-called athletic anorexia or the RED-S. </p> Conclusions:It is important to emphasize that not only do professional athletes suffer from it, but also good-looking amateurs and amateurs. 31684854 2020
Entrez Id: 3550
Gene Symbol: IK
IK
0.010 Biomarker group BEFREE </p> Results:In general, nutrition is experienced, not only by athletes themselves but also by technicians and coaches, as a tool for improving performance and as such assimilated to an aspect of training but in the presence of factors of vulnerability towards the ED by of the young athletes the exaggerated tendency to manipulate the weight can determine the appearance of an eating disorder or of the so-called athletic anorexia or the RED-S. </p> Conclusions:It is important to emphasize that not only do professional athletes suffer from it, but also good-looking amateurs and amateurs. 31684854 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.100 AlteredExpression group BEFREE Reduced plasma BDNF levels have also been reported in patients with eating disorders and obesity. 31004714 2019
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.100 PosttranslationalModification group BEFREE Increased rsFC in the salience network mediated the link between SLC6A4 methylation and eating disorder symptoms in patients with anorexia nervosa. 31804778 2019
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.100 PosttranslationalModification group BEFREE Increased rsFC in the salience network mediated the link between SLC6A4 methylation and eating disorder symptoms in patients with anorexia nervosa. 31823595 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.100 GeneticVariation group BEFREE Evidence suggests that the most frequent single nucleotide polymorphism (SNP) of BDNF gene (rs6265) has been associated with different psychiatric, neurodegenerative and eating disorders. 30602138 2019
Entrez Id: 6886
Gene Symbol: TAL1
TAL1
0.090 Biomarker group BEFREE All participants completed the Self-Compassion Scale (SCS), Hopkins Symptom Checklist (SCL-5), Body Areas Satisfaction Scale (BASS), and Eating Disorder Examination Questionnaire - Adolescent Version (EDE-Q) at baseline. 30977532 2019
Entrez Id: 3855
Gene Symbol: KRT7
KRT7
0.090 GeneticVariation group BEFREE Adult inpatients (<i>n</i> = 166) with longstanding DSM-IV Anorexia Nervosa, Bulimia Nervosa (BN) or Eating Disorder not Otherwise Specified (EDNOS) completed the CET instrument, Eating Disorder examination questionnaire (EDE-Q), Beck Depression Inventory-II (BDI-II) and Symptom checklist-90 (SCL-90). 31695652 2019
Entrez Id: 51540
Gene Symbol: SCLY
SCLY
0.090 GeneticVariation group BEFREE Adult inpatients (<i>n</i> = 166) with longstanding DSM-IV Anorexia Nervosa, Bulimia Nervosa (BN) or Eating Disorder not Otherwise Specified (EDNOS) completed the CET instrument, Eating Disorder examination questionnaire (EDE-Q), Beck Depression Inventory-II (BDI-II) and Symptom checklist-90 (SCL-90). 31695652 2019
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.090 Biomarker group BEFREE A pragmatic effectiveness study of 10-session cognitive behavioural therapy (CBT-T) for eating disorders: Targeting barriers to treatment provision. 31134731 2019
Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
0.090 GeneticVariation group BEFREE Results suggest that adolescents with BN who are more motivated to change OC-ED behaviours at the start of treatment, FBT-BN or CBT-A, are more likely to demonstrate improvements in cognitions, but not behaviours associated with EDs, at treatment conclusion. 30734406 2019
Entrez Id: 3855
Gene Symbol: KRT7
KRT7
0.090 Biomarker group BEFREE All participants completed the Self-Compassion Scale (SCS), Hopkins Symptom Checklist (SCL-5), Body Areas Satisfaction Scale (BASS), and Eating Disorder Examination Questionnaire - Adolescent Version (EDE-Q) at baseline. 30977532 2019
Entrez Id: 6886
Gene Symbol: TAL1
TAL1
0.090 GeneticVariation group BEFREE Adult inpatients (<i>n</i> = 166) with longstanding DSM-IV Anorexia Nervosa, Bulimia Nervosa (BN) or Eating Disorder not Otherwise Specified (EDNOS) completed the CET instrument, Eating Disorder examination questionnaire (EDE-Q), Beck Depression Inventory-II (BDI-II) and Symptom checklist-90 (SCL-90). 31695652 2019
Entrez Id: 51540
Gene Symbol: SCLY
SCLY
0.090 Biomarker group BEFREE All participants completed the Self-Compassion Scale (SCS), Hopkins Symptom Checklist (SCL-5), Body Areas Satisfaction Scale (BASS), and Eating Disorder Examination Questionnaire - Adolescent Version (EDE-Q) at baseline. 30977532 2019
Entrez Id: 4170
Gene Symbol: MCL1
MCL1
0.090 GeneticVariation group BEFREE Global scores on the Eating Attitudes Test-26 (EAT-26), Eating Disorder Examination Questionnaire (EDEQ), and Eating Disorder Diagnostic Scale for DSM-IV (EDDS) were examined. 31233228 2019
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.060 Biomarker group BEFREE Accordingly, the aim of this article is to review the current state of the art of leptin in relation to AN to provide the theoretical basis for the initiation of clinical trials for treatment of this eating disorder. 31156489 2019
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
0.060 GeneticVariation group BEFREE The aim of the present study was to analyze the association of rs6311 and rs6313 polymorphisms of 5-HTR2A gene with eating disorders in Mexican population, and to evaluate if the polymorphisms of 5-HTR2A gene were associated with comorbidities in eating behavior. 31199591 2019
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.060 Biomarker group BEFREE Further studies investigating the role of leptin in impulsive behaviors in eating disorders would be useful. 31125904 2019
Entrez Id: 100653365
Gene Symbol: BED
BED
0.050 GeneticVariation group BEFREE The 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions-III (N=36,309) included respondents who met the criteria for specific lifetime DSM-5 EDs and answered questions regarding help-seeking for their ED symptoms (anorexia nervosa [AN]: n=275; bulimia nervosa [BN]: n=91; and binge-eating disorder [BED]: n=256). 31324401 2019
Entrez Id: 100653365
Gene Symbol: BED
BED
0.050 Biomarker group BEFREE Many clinical variables were higher among patients with secretive eating compared to those without secretive eating; however, only eating disorder psychopathology severity and body dissatisfaction remained significantly higher among patients with secretive eating compared to those without when bariatric BED status was also included as a variable in the model. 31033037 2019